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[IF=8.44] Li Xiangdong. et al. Hepatocyte SGK1 activated by hepatic ischemia-reperfusion promotes the recurrence of liver metastasis via IL-6/STAT3. J TRANSL MED. 2023 Dec;21(1):1-19  IHC,IF,WB ;  Mouse.  

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[IF=6.63] Guo, Zhi-chen. et al. Porphyromonas gingivalis promotes the progression of oral squamous cell carcinoma by activating the neutrophil chemotaxis in the tumour microenvironment. CANCER IMMUNOL IMMUN. 2022 Dec;:1-17  WB ;  Mouse.  

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[IF=6.317] Qin Yang. et al. Anti-tumor effect of infant-derived Enterococcus via the inhibition of proliferation and inflammation as well as the promotion of apoptosis. FOOD FUNCT. 2023 Jan;:  WB ;  Mouse.  

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[IF=5.279] Yan Zhang. et al. Ganoderic Acid A To Alleviate Neuroinflammation of Alzheimer’s Disease in Mice by Regulating the Imbalance of the Th17/Tregs Axis. J Agr Food Chem. 2021;69(47):14204–14214  WB ;  Mouse.  

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[IF=5.195] Yong Wang. et al. An integrated network pharmacology approach reveals that Darutigenol reduces inflammation and cartilage degradation in a mouse collagen-induced arthritis model by inhibiting the JAK-STAT3 pathway. J ETHNOPHARMACOL. 2023 May;:116574  WB ;  Mouse.  

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[IF=5.037] Hongwu Meng. et al. Interleukin-9 attenuates inflammatory response and hepatocyte apoptosis in alcoholic liver injury. Life Sci. 2022 Jan;288:120180  WB ;  Mouse.  

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[IF=4.868] Wang G et al. Protective?Effect?of?Methane-Rich?Saline?on?Acetic?Acid-Induced?Ulcerative?Colitis?via?Blockingthe?TLR4/NF-κB/MAPK?Pathway?and?Promoting?IL-10/JAK1/STAT3-Mediated Anti-inflammatory Response. Oxid Med Cell Longev.?2019 Apr 28;2019:7850324.  WB ;  Mouse.  

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[IF=4.187] Jiajia Wang. et al. TAK-242 ameliorates DSS-induced colitis by regulating the gut microbiota and the JAK2/STAT3 signaling pathway. Microb Cell Fact. 2020 Dec;19(1):1-17  WB ;  Mouse.  

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[IF=4.105] Ai Jin. et al. TSLP-induced collagen type-I synthesis through STAT3 and PRMT1 is sensitive to calcitriol in human lung fibroblasts. Bba-Mol Cell Res. 2021 Jun;:119083  WB ;  Human.  

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[IF=3.606] Xuejiao Zhou. et al. The novel ALK inhibitor ZX‐29 induces apoptosis through inhibiting ALK and inducing ROS‐mediated endoplasmic reticulum stress in Karpas299 cells. 2020 Nov 02  WB ;  Human.  

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[IF=3.457] Ling L et al. MicroRNA-30e promotes hepatocyte proliferation and inhibits apoptosis in cecal ligation and puncture-induced sepsis through the JAK/STAT signaling pathway by binding to FOSL2.Biomed Pharmacother. 2018 Aug;104:411-419.  WB ;  Rat.  

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[IF=3.414] Zhou H et al. Paris saponin VII extracted from trillium tschonoskii suppresses proliferation and induces apoptosis of human colorectal cancer cells. J Ethnopharmacol.?2019 Jul 15;239:111903.  WB ;  Human.  

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[IF=3.411] Feng Junlong. et al. Explore the Effect of Asthma Regulating HIF-1 Pathway on Sperm Quality Based on Rat Model. BIOMED RES INT. 2022;2022:4194685  WB ;  Rat.  

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[IF=3.36] Iriyama et al. Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes. (2016) Cancer.Med. 5:3223-3234  FC/FACS ;  Human.  

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[IF=3.347] Yuying Li. et al. Anthraquinone derivative C10 inhibits proliferation and cell cycle progression in colon cancer cells via the Jak2/Stat3 signaling pathway. Toxicol Appl Pharm. 2021 Mar;:115481  IF ;  Human.  

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[IF=3.287] Keliang Song. et al. Knocking down Siglec-15 in osteosarcoma cells inhibits proliferation while promoting apoptosis and pyroptosis by targeting the Siglec-15/STAT3/Bcl-2 pathway. ADV MED SCI-POLAND. Adv Med Sci-Poland. 2022 Sep;67:187  WB ;  Human.  

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[IF=3.269] Leiming Sun. et al. Isoliquiritigenin attenuates acute renal injury through suppressing oxidative stress, fibrosis and JAK2/STAT3 pathway in streptozotocin-induced diabetic rats. Bioengineered. 2021;12(2):11188-11200  WB ;  Rat.  

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[IF=3.23] Lee E-J, Lee SJ, Kim J-H, Kim K-J, Yang S-H, Jeong K-Y, et al. (2016) Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells. PLoS ONE 11(1): e0146463.  WB ;  Mouse.  

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[IF=3.23] Sur, Swastika, et al. "Increased Expression of Phosphorylated Polo-Like Kinase 1 and Histone in Bypass Vein Graft and Coronary Arteries following Angioplasty." PloS one 11.1 (2016): e0147937.  IF(IHC-P) ;  Pig.  

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[IF=2.991] Yang?L et al. 15-Lipoxygenase-2/15(S)-hydroxyeicosatetraenoic acid regulates cell proliferation and metastasis via the STAT3 pathway in lung adenocarcinoma. Prostaglandins Other Lipid Mediat. 2018 Sep;138:31-40.  WB&IHC-P ;  Human.  

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[IF=2.886] Yusi Liu. et al. Synergistic Effects of Resveratrol and Temozolomide Against Glioblastoma Cells: Underlying Mechanism and Therapeutic Implications. Cancer Manag Res. 2020; 12: 8341–8354  ICC ;  Rat, Human.  

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[IF=2.838] Huang Yongpan. et al. Oxymatrine ameliorates myocardial injury by inhibiting oxidative stress and apoptosis via the Nrf2/HO-1 and JAK/STAT pathways in type 2 diabetic rats. BMC Complementary Medicine and Therapies. 2023 Dec;23(1):1-13  WB ;  Rat.  

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[IF=2.82] Gao, Ling, et al. "Morusin shows potent antitumor activity for human hepatocellular carcinoma in vitro and in vivo through apoptosis induction and angiogenesis inhibition." Drug Design, Development and Therapy 11 (2017): 1789.  WB ;  Human.  

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[IF=2.81] Badin et al. Muscle Arnt/Hif1β Is Dispensable in Myofiber Type Determination, Vascularization and Insulin Sensitivity. (2016) PLoS.One. 11:e0168457  WB ;  Mouse.  

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[IF=2.736] Hao Y et al. IL-6/STAT3 mediates the HPV18 E6/E7 stimulated upregulation of MALAT1 gene in cervical cancer HeLa cells. Virus Res. 2020 May;281:197907.  WB ;  human.  

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[IF=2.705] Li B et al. Increased hepcidin in hemorrhagic plaques correlates with iron-stimulated IL-6/STAT3 pathway activation in macrophages. Biochem Biophys Res Commun. 2019 Jul 23;515(2):394-400.  IHC,WB ;  Rabbit,Human&Mouse.  

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[IF=2.559] Bi?J et al. PPARγ alleviated hepatocyte steatosis through reducing SOCS3 by inhibiting JAK2/STAT3 pathway. Biochem Biophys Res Commun. 2018 Apr 15;498(4):1037-1044.  ICC&WB ;  Rat.  

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[IF=2.51] Yang, Hai Li, et al. "Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte." Molecular biology reports 39.9 (2012): 9113-9122.  WB ;  Pig.  

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[IF=2.25] Li?H et al. MicroRNA-204-5p suppresses IL6-mediated inflammatory response and chemokine generation in HK-2 renal tubular epithelial cells by targeting IL6R. Biochem Cell Biol. 2019 Apr;97(2):109-117.  WB ;  Human.  

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