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NXT1 Rabbit pAb (bs-19556R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-19556R
英文名稱 NXT1 Rabbit pAb
中文名稱 核運輸因子1抗體
別    名 MTR2; MTR2, yeast, homolog of; NTF2 like export factor 1; NTF2 related export protein 1; NTF2-related export protein 1; NUTF like export factor 1; NXT1; NXT1_HUMAN; P15; Protein P15.  
研究領(lǐng)域 染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow)
產(chǎn)品應(yīng)用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 16 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human NXT1: 51-140/140 
亞    型
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with THOC4 and THOC5.

Subcellular Location:
Nucleus. Cytoplasm. Shuttles between the nucleus and the cytoplasm.

Similarity:
Contains 1 NTF2 domain.

SWISS:
Q9UKK6

Gene ID:
29107

Database links:

Entrez Gene: 29107 Human

Entrez Gene: 520351 Cow

Entrez Gene: 56488 Mouse

Entrez Gene: 296219 Rat

Omim: 605811 Human

SwissProt: Q2KIW0 Cow

SwissProt: Q9UKK6 Human

SwissProt: Q9QZV9 Mouse

Unigene: 516933 Human

Unigene: 34663 Mouse

Unigene: 8541 Rat



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