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human CD25/PE (bsm-30077M-PE)  
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25T/1380.00元
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產(chǎn)品編號 bsm-30077M-PE
英文名稱 human CD25/PE
中文名稱 PE標(biāo)記人CD25單克隆抗體
別    名 Interleukin 2 receptor alpha chain; CD 25; CD25; CD25 antigen; IDDM10; IL 2 RA; IL 2 receptor alpha subunit; IL2 RA; IL-2RA; IL2R; IL2RA; IL2RAC; Interleukin 2 Receptor Alpha; Interleukin 2 receptor alpha chain; Interleukin 2 receptor; Ly43; p55; T Cell Growth Factor Receptor; TAC Antigen; TCGFR; IL2RA_HUMAN.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  細(xì)胞膜受體  淋巴細(xì)胞  t-淋巴細(xì)胞  b-淋巴細(xì)胞  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 HI25a
交叉反應(yīng)
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 28kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
亞    型 IgG
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq, Nov 2009].

Function:
Receptor for interleukin-2.

Subunit:
Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Similarity:
Contains 2 Sushi (CCP/SCR) domains.

SWISS:
P01589

Gene ID:
3559

Database links:

Entrez Gene: 3559 Human

SwissProt: P01589 Human

Unigene: 231367 Human

Omim: 147730 Human



產(chǎn)品圖片
Flow cytometry staining of normal human peripheral blood cells with CD25/PE(bsm-30077M-PE)(Red histogram) or Mouse IgG1 Isotype Control (PE Conjugate)(C03-11002 )(Blue histogram) . Total cells were used for analysis.
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