亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
1a级毛片免费观看,a无码亚洲男人的天堂,一级毛片人与动免费观看
首頁 > 產(chǎn)品中心 > 一抗 > 產(chǎn)品信息
RAB5B Mouse mAb (bsm-51720M)  
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
50ul/1180.00元
100ul/1980.00元
大包裝/詢價

產(chǎn)品編號 bsm-51720M
英文名稱 RAB5B Mouse mAb
中文名稱 RAS相關(guān)蛋白Rab5B單克隆抗體
別    名 Rab 5b; Rab5 b; RAB5B, member RAS oncogene family; Ras related protein Rab 5B; RAB5B_HUMAN.  
研究領(lǐng)域 染色質(zhì)和核信號  表觀遺傳學(xué)  泛素  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 D4F6
交叉反應(yīng) Human,Mouse
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 24 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human RAB5B. 
亞    型 IgG1,Κ
純化方法 affinity purified by Protein G
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology with Ras p21. Accumulating data suggests an important role for Rab proteins, either in endocytosis or in biosynthetic protein transport. The transport of newly synthesized proteins from the endoplasmic reticulum to various stacks of the Golgi complex and to secretory vesicles involves at each stage the movement of carrier vesicles, a process that appears to involve Rab protein function. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40% homologous to Rab proteins, is associated with secretory vesicles. At least eight members of the Rab subfamily have been identified, each of which is found at a particular stage of a membrane transport pathway.

Function:
Rab5b is a member of the Rab family of small (monomeric) G proteins. Like other small G proteins, Rab5b switches between an inactive, GDP-form and an active, GTP-bound form. GDP/GTP exchange factors (GEFs) catalyse the conversion from the GDP-bound form to the GTP-bound form, while GTPase-activating proteins (GAPs) catalyse GTP hydrolysis to GDP. Rab5b is involved in endocytosis and recycling of cell surface molecules. It interacts with RIN2 and RIN3, which regulate its function, possibly by acting as GEFs. Knockdown of Rab5b abolished group I metabotropic glutamate receptor (mGluR)-mediated neuroprotection. Furthermore, Rab5b interacts with LRRK2, the defective gene at the PARK8 locus that results in Parkinson's disease. Roles for Rab5b in neurodegenerative disease, neuroprotection, and synaptic plasticity have been suggested.

Subunit:
Binds EEA1. Interacts with RIN2 and RIN3, which probably regulate its pathway, possibly by acting as GEFs.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side. Early endosome membrane; Lipid-anchor. Melanosome. Note=Enriched in stage I melanosomes.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

SWISS:
P61020

Gene ID:
5869

Database links:

Entrez Gene: 5869 Human

SwissProt: P61020 Human



產(chǎn)品圖片
Sample: Lane 1: Hela cell lysates Lane 2: HepG2 cell lysates Lane 3: Jurkat cell lysates Lane 4: NIH-3T3 cell lysates Primary: Anti-RAB5B (bsm-51720M) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 26 kD
Sample: Lane 1: A431 cell lysates Primary: Anti-RAB5B (bsm-51720M) at 1/2000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 24 kD Observed band size: 24 kD
版權(quán)所有 2004-2026 m.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
第九色区av天堂 | 国产精品内射久久久久欢欢 | 一本久道久久综合婷婷五月 | 久久久久久亚洲AV无码被处 | 嫩草在线视频WWW免费看 | 欧美一级婬人妻欧美大片 | 国产精品视频一区二区三区 | 久久精品99久久久久久蜜芽TV | 情浓野战台湾三级 | 精品黄毛片久久99国产 | 中文字幕永久天天综合 | ANGELINA全集在线播放 | 国产精品久久久久久精品毛片 | 粉粉嫩嫩bbbxx | 久久夜色精品国产噜噜亚洲av | 伊人久久大香线蕉AV一区二 | 久久综合九色综合91 | 亚洲国产精品一区二区动图 | 日本内射精品一区二区视频 | 好爽毛片一区二区三区色欲 | 算你色永久免费视频播放 | 精品国产污污免费网站入口在线 | 国产福利91精品一区二区三区 | 免费一级毛片在线观看 | 国产午夜亚洲精品国产 | 国产一区二区三区视频 | 欧美日韩无线码一区茄子视频 | 成人午夜国产内射主播 | 中文字幕无码中文字幕有码 | 天天做天天爱天天爽综合网 | 99精品无人区乱码在线观看 | 中文字幕不卡一区二区三区 | 真人插B免费视频播放 | 91精品国产综合久久久久久 | 欧美日韩一区二区三区四区 | 久久精品午夜一区二区福利 | 欧美高清免费精品国产自 | 五十丰满熟妇性旺盛 | 国产午夜影视大全免费观看 | 精品自拍视频五区六区在线观看 | 国产狂喷水潮免费网站www |