| 產品編號 | V5513 |
| 英文名稱 | NF-L Rabbit mAb |
| 中文名稱 | 低分子量神經絲蛋白單克隆抗體 |
| 別 名 | Neurofilament L; Neurofilament 68; Neurofilament triplet L; 70 kD Neurofilament Light; 68kDa neurofilament protein; CMT 1F; CMT 2E; CMT1F; CMT2E; FLJ53642; Light molecular weight neurofilament protein; NEFL; Neurofilament light; Neurofilament light polype |
| 克 隆 號 | 5B2 |
| 理論分子量 | 68kDa |
| 性 狀 | Liquid |
| 純 度 | >90% as determined by SDS-PAGE |
| 緩 沖 液 | 0.01M PBS(pH7.4) |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產品介紹 |
Neurofilament light polypeptide also called NF-L; Neurofilament triplet L protein; 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family. SWISS: P07196 Gene ID: 4747 神經生物學相關蛋白（Neurobiology） 低分子量神經絲蛋白,簡稱NF-L,分子量為68kDa，NF-L的聚集與神經退行性疾病的發(fā)病機理相關，如運動神經元的降解等。 神經纖絲蛋白的功能是提供彈性使神經纖維易于伸展和防止斷裂。 神經絲是中間纖維的一種重要類型又稱神經微絲蛋白，特異地在神經細胞內表達，并在軸突內相互平行排列成束. 哺乳動物的神經絲由3種蛋白組成： 低分子量神經絲蛋白，簡稱NF-L；分子量為68kDa； 中分子量神經絲蛋白，簡稱NF-M；分子量為160kDa； 高分子量神經絲蛋 |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
