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Rabbit Anti-RAR gamma/BF488 Conjugated antibody (bs-6218R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-6218R-BF488
英文名稱 Rabbit Anti-RAR gamma/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的維甲酸受體γ抗體
別    名 NR1B3; Nuclear receptor subfamily 1 group B member 3; RAR gamma; RARC; RARG; Retinoic acid receptor gamma 1; Retinoic acid receptor gamma 2; Retinoic acid receptor gamma; Retinoic acid receptor gamma polypeptide; Retinoic acid receptor, gamma; RARG_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 50kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Retinoic Acid Receptor gamma
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Retinoic acid, a metabolite of vitamin A, is necessary for normal organogenesis but acts as a teratogen at high levels during embryonic and fetal development. Retinoic acid functions through its interaction with the nuclear protein, retinoic acid receptor (RAR). RAR belongs to the steroid and thyroid hormone superfamily of nuclear receptor proteins which exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. RAR exists as three major subtypes: alpha, beta and gamma.

Subunit:
Homodimer. Heterodimer with a RAR molecule (By similarity). Binds DNA preferentially as a RAR/RXR heterodimer.

Subcellular Location:
Nucleus.

Similarity:
Belongs to the nuclear hormone receptor family. NR2 subfamily.
Contains 1 nuclear receptor DNA-binding domain.

Database links:

Entrez Gene: 540425 Cow

Entrez Gene: 5916 Human

Entrez Gene: 19411 Mouse

Entrez Gene: 685072 Rat

Omim: 180190 Human

SwissProt: P13631 Human

SwissProt: P18911 Mouse

Unigene: 1497 Human

Unigene: 733399 Human

Unigene: 1273 Mouse

Unigene: 198797 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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