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Rabbit Anti-CD82/Gold Conjugated antibody (bs-1470R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1470R-Gold
英文名稱 Rabbit Anti-CD82/Gold Conjugated antibody
中文名稱 膠體金標記的腫瘤轉(zhuǎn)移抑制蛋白1抗體
別    名 4F9; Antigen detected by monoclonal and antibody IA4; C33; C33 antigen; CD 82; CD82 antigen; CD82 molecule; GR 15; GR15; IA 4; IA4; Inducible membrane protein; Inducible membrane protein R2; KAI 1; KAI1; Kangai 1; Kangai1; Metastasis suppressor Kangai 1; Metastasis suppressor Kangai1; R2 leukocyte antigen; CD82_HUMAN.   
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領(lǐng)域 腫瘤  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  細胞表面分子  細胞類型標志物  t-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應(yīng)用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD82
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway.

Subunit:
Interacts directly with IGSF8.

Subcellular Location:
Membrane.

Tissue Specificity:
Lymphoid specific.

Similarity:
Belongs to the tetraspanin (TM4SF) family.

Database links:

Entrez Gene: 3732 Human

Entrez Gene: 12521 Mouse

Entrez Gene: 83628 Rat

Omim: 600623 Human

SwissProt: P27701 Human

SwissProt: P40237 Mouse

SwissProt: O70352 Rat

Unigene: 527778 Human

Unigene: 4261 Mouse

Unigene: 3022 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

信號傳導(dǎo)(Signaling Intermediates)
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