亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲AV无一区二区三区 ,欧美日韩成人VA精品一区二区三区不卡 ,在线播放连续内射爽翻天vol
Rabbit Anti-phospho-ATF2 (Ser490/498)/PE-Cy5 Conjugated antibody (bs-1648R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1648R-PE-Cy5
英文名稱 Rabbit Anti-phospho-ATF2 (Ser490/498)/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的磷酸化活化復(fù)制因子2抗體
別    名 ATF2 (phospho S490); p-ATF2 (phospho S490); ATF2 (phospho S490 + S498); p-ATF2 (phospho S490 + S498); CREB 2; HB 16;Activating Transcription Factor 2; ATF 2; Atf-2; ATF2 protein; cAMP Response Element Binding Protein 2; cAMP response element binding protein CRE BP1; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; CRE BP1; CRE-BP; CREB 2; CREB2; CREBP1; Cyclic AMP dependent transcription factor ATF 2; Cyclic AMP-responsive.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  免疫學(xué)  染色質(zhì)和核信號  信號轉(zhuǎn)導(dǎo)  細(xì)胞凋亡  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human ATF2 around the phosphorylation site of Ser490/498
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
ATF2 is a member of the ATF/CREB family of basic region leucine zipper DNA binding proteins that regulates transcription by binding to a consensus cAMP response element (CRE) in the promoter of various viral and cellular genes. Many of these genes are important in cell growth and differentiation, and in stress and immune responses. ATF2 is a nuclear protein that binds DNA as a dimer and can form dimers with members of the ATF/CREB and Jun/Fos families. It is a stronger activator as a heterodimer with cJun than as a homodimer. Several isoforms of ATF2 arise by differential splicing. The stable native full length ATF2 is transcriptionally inactive as a result of an inhibitory direct intramolecular interaction of its carboxy terminal DNA binding domain with the amino terminal transactivation domain. Following dimerization ATF2 becomes a short lived protein that undergoes ubiquitination and proteolysis, seemingly in a protein phosphatase-dependent mechanism. Stimulation of the transcriptional activity of ATF2 occurs following cellular stress induced by several genotoxic agents, inflammatory cytokines, and UV irradiation. This activation requires phosphorylation of two threonine residues in ATF2 by both JNK/SAP kinase and p38 MAP kinase. ATF2 is abundantly expressed in brain.

Subunit:
Binds DNA as a dimer and can form a homodimer in the absence of DNA. Can form a heterodimer with JUN. Interacts with SMAD3 and SMAD4. Binds through its N-terminal region to UTF1 which acts as a coactivator of ATF2 transcriptional activity.

Subcellular Location:
Nucleus.

Tissue Specificity:
Abundant expression seen in the brain.

Similarity:
Belongs to the bZIP family. ATF subfamily.
Contains 1 bZIP domain.
Contains 1 C2H2-type zinc finger.

Database links:

Entrez Gene: 1386 Human

Entrez Gene: 100047997 Mouse

Entrez Gene: 11909 Mouse

Entrez Gene: 81647 Rat

Omim: 123811 Human

SwissProt: P15336 Human

SwissProt: P16951 Mouse

SwissProt: Q00969 Rat

Unigene: 592510 Human

Unigene: 209903 Mouse

Unigene: 9825 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

轉(zhuǎn)錄調(diào)節(jié)因子(Transcriptin Regulators)
版權(quán)所有 2004-2026 m.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
一本久久a久久精品免费不卡 | 国产乱婬AV一区二区三区 | 亚洲国产天堂99精品一区 | 国产麻豆精品久久一二三 | 最近最新免费手机中文 | 亚洲欧美一区二区三区孕妇写真 | 狠狠色噜噜狠狠狠7777 | 国产高清视频免费最新在线 | 亚洲伊人久久综合影院2021 | 人妻仑乱A级毛片免费看 | 久99视频精品免费观看福利 | 国产GAYSEXCHINA男外卖 | 最近中文字幕MV免费高清动漫 | 1000部夫妻午夜免费 | 欧美日韩一区二区三区自拍 | 九九热线有精品视频99 | 日本一二三区在线视频 | 真实的国产乱xxxx在线 | 免费午夜无码18禁无码影视 | 91免费精品国自产拍在线不卡 | 狼人香蕉香蕉在线28 | 一级欧美一级日韩 | 国产女人乱人伦精品一区二区 | 少妇被又大又粗又爽毛片久久黑人 | 国产精品手机在线无码援交 | 91精品国产色综合久久不卡美美 | 毛av毛aⅴ毛aaa正片 | 在线欧美精品一区二区三区 | 久久午夜一区二区 | 五月丁香久久伊人本道开心 | 91精品久久久久久久久久 | 久久人人爽人人人爽成人AV片 | 精品国产在天天线在线 | 中文精品一区二区三区四区 | 一级毛片在线免费视频 | 国产精品 视频 | 国产精品福利电影 | 毛片无码免费无码播放 | 国产亚洲精品女人久久久久久 | 高潮毛片无遮挡高清免费视频 | 亚洲国产欧美中日韩成人综合视频 |