| 產(chǎn)品編號(hào) | bs-7826R-AP |
| 英文名稱 | Rabbit Anti-RABGAP1/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的Rab蛋白GTP酶激活蛋白1抗體 |
| 別 名 | Rab GTPase-activating protein 1; Rab GAP1, GAP and centrosome associated protein; HSPC094; Rab GTPase activating protein 1; Rab6 GTPase activating protein GAPCenA; RBGP1_HUMAN. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞周期蛋白 細(xì)胞類型標(biāo)志物 G蛋白信號(hào) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 122kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RABGAP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Rab GTPase-activating protein 1 is a 1,069 amino acid cytoplasmic protein containing one PID domain and one Rab-GAP TBC domain. Rab GAP1 acts as a GTPase-activating protein of Rab 6A in the Rab 6A-mediated pathway, which is involved in the metaphase-anaphase transition. Expressed as four alternatively spliced variants, Rab GAP1 may also be involved in the microtubule nucleation by centrosome and in Golgi dynamics during the cell cycle. Rab GAP1 is encoded by a gene located on human chromosome 9, which consists of about 145 million bases, 4% of the human genome and encodes nearly 900 genes. Function: May act as a GTPase-activating protein of RAB6A. Mayplay a role in microtubule nucleation by centrosome. Mayparticipate in a RAB6A-mediated pathway involved in themetaphase-anaphase transition. Subunit: Interacts with RAB6A and tubulin gamma. Subcellular Location: Cytoplasm, cytosol. Cytoplasm, cytoskeleton,centrosome. Note=Predominantly cytosolic but also associated withthe centrosome. Similarity: Contains 1 PID domain. Contains 1 Rab-GAP TBC domain. Database links: Entrez Gene: 23637 Human Entrez Gene: 227800 Mouse SwissProt: Q9Y3P9 Human SwissProt: A2AWA9 Mouse Unigene: 271341 Human Unigene: 383192 Mouse Unigene: 14944 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
