| 產(chǎn)品編號 | bs-16782R-BF488 |
| 英文名稱 | Rabbit Anti-KLRC4/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的殺傷細(xì)胞凝集素樣受體C亞家族成員4抗體 |
| 別 名 | killer cell lectin-like receptor subfamily C, member 4; KLRC4; NK cell receptor F; NKG2 F; NKG2-F type II integral membrane protein; NKG2-F-activating NK receptor; NKG2F; NKG2F_HUMAN. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 自然殺傷細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human KLRC4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. This gene is a member of the NKG2 group of genes that are expressed primarily in natural killer (NK) cells. These family members encode transmembrane proteins that are characterized by a type II membrane orientation (have an extracellular C-terminus) and the presence of a C-type lectin domain. This family member is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. Read-through transcription exists between this gene and the downstream KLRK1 (killer cell lectin-like receptor subfamily K, member 1) family member. [provided by RefSeq, Dec 2010] Function: May play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells. Subunit: Can form disulfide-bonded heterodimer with CD94. Subcellular Location: Membrane. Tissue Specificity: Natural killer cells. Database links: Entrez Gene: 8302 Human Omim: 602893 Human SwissProt: O43908 Human Unigene: 721094 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
