亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
波多野结衣被躁57分钟,爆乳JK美女脱内衣裸体网站
Rabbit Anti-COPS3/HRP Conjugated antibody (bs-23085R-HRP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23085R-HRP
英文名稱 Rabbit Anti-COPS3/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標(biāo)記的COP9信號(hào)復(fù)合體亞基3抗體
別    名 COP9 Signalosome Complex Subunit 3; CSN10; JAB1 Containing Signalosome Subunit 3; SGN3; Signalosome Subunit 3; CSN3_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  細(xì)胞周期蛋白  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 48kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COPS3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].

Function:
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Subunit:
Component of the CSN complex, composed of COPS1/GPS1, COPS2, COPS3, COPS4, COPS5, COP6, COPS7 (COPS7A or COPS7B) and COPS8. In the complex, it probably interacts directly with COPS1, COPS4 and COPS8. Interacts with CK2 and PKD. Interacts with the translation initiation factor EIF3S6 and IKBKG.

Subcellular Location:
Cytoplasmic and Nuclear.

Tissue Specificity:
Widely expressed. Expressed at high level in heart and skeletal muscle.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the CSN3 family.
Contains 1 PCI domain.

Database links:

Entrez Gene: 8533 Human

Entrez Gene: 26572 Mouse

Entrez Gene: 287367 Rat

Omim: 604665 Human

SwissProt: Q9UNS2 Human

SwissProt: O88543 Mouse

SwissProt: Q68FW9 Rat

Unigene: 6076 Human

Unigene: 40 Mouse

Unigene: 3963 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 m.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
欧美激情性AAAAA片 | 欧美亚洲清纯国产综合图区 | 国产成人精品日本亚洲11 | 午夜精品久久久久久久99热 | 中文字幕欧美一区 | yy6080影院色呦呦私人 | q2002午夜我的老师 | 免费国产成人高清在线视频 | 久99久热只有精品国产99 | 免费黄色网站在线观看 | 国产精品久久久久久无码 | 国产精品亚洲二线在线播放 | 久久国产精品99久久久久久老狼 | 亚洲色婷婷综合久久二区 | 99re免费观看国产在线观看 | 国产精品国产三级国产an | 2020精品极品国产色在线观看 | 日韩一区二区超清视频 | 情趣白丝女仆下部被揉小说合集 | 风流少妇又紧又爽又丰满 | 亚洲最大日夜无码中文字幕 | 亚洲国产精品无码久久久久久曰 | 欧美日韩一区二区三区人妻 | 麻豆精产国品免费免费观看高清 | 人妻内射一区二区在线视频 | 亚洲中文字幕无码中文字 | 先峰中文字幕一二三区 | 人妻少妇精品无码专区喷水 | 亚洲欧美国产双大乳头 | 亚洲欧美一区二区三区图片 | 婷婷六月激情综合一区 | 牛牛本精品99久久精品88m | 久久99精品久久久久久园产越南 | 真人与拘做受免费视频 | 综合一区二区自拍亚洲 | 把手戳进美女尿口里动态图 | 91精品国产自产在线观看 | 国产成人91亚洲精品无码观看 | 好紧好爽好疼的免费视频全集完整版在线播放 | 看亚洲A级一级毛片,亚洲AV片 | 精品亚洲国产成AV人片传媒 |