亚洲制服欧美另类-午夜激情av电影-日本高清中文字幕一区二区三区-中国欧美日韩一区二区三区-欧洲亚洲日本韩国-成人欧美激情一区二区-亚洲偷偷自拍高清

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
黑巨人与欧美精品一区,成人H动漫精品一区二区,国产大片在线播放
Rabbit Anti-VEGF-A/PE-Cy5 Conjugated antibody (bs-23255R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-23255R-PE-Cy5
英文名稱 Rabbit Anti-VEGF-A/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標(biāo)記的血管內(nèi)皮生長因子A抗體
別    名 Vascuoar endothelial growth factor A; VEGF A; vascular endothelial growth factor A isoform 2 precursor; Vegf; VEGFA; MGC70609; MVCD1; VEGF; VPF; VEGFA_HUMAN; Vascular endothelial growth factor A; VEGF-A; Vascular permeability factor; VPF; VEGF A Precursor.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  心血管  信號(hào)轉(zhuǎn)導(dǎo)  生長因子和激素  血管內(nèi)皮細(xì)胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Dog, Pig, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 24kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human VEGF-A
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.

Function:
Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform VEGF165B binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth.

Subunit:
Homodimer; disulfide-linked. Also found as heterodimer with PGF (By similarity).

Subcellular Location:
Secreted. Note=VEGF121 is acidic and freely secreted. VEGF165 is more basic, has heparin-binding properties and, although a signicant proportion remains cell-associated, most is freely secreted. VEGF189 is very basic, it is cell-associated after secretion and is bound avidly by heparin and the extracellular matrix, although it may be released as a soluble form by heparin, heparinase or plasmin.

Tissue Specificity:
Isoform VEGF189, isoform VEGF165 and isoform VEGF121 are widely expressed. Isoform VEGF206 and isoform VEGF145 are not widely expressed.

DISEASE:
Defects in VEGFA are a cause of susceptibility to microvascular complications of diabetes type 1 (MVCD1) [MIM:603933]. These are pathological conditions that develop in numerous tissues and organs as a consequence of diabetes mellitus. They include diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease, and diabetic neuropathy. Diabetic retinopathy remains the major cause of new-onset blindness among diabetic adults. It is characterized by vascular permeability and increased tissue ischemia and angiogenesis.

Similarity:
Belongs to the PDGF/VEGF growth factor family.

Database links:

Entrez Gene: 7422 Human

Entrez Gene: 22339 Mouse

Omim: 192240 Human

SwissProt: P15692 Human

SwissProt: Q00731 Mouse

Unigene: 73793 Human

Unigene: 282184 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生長因子和激素(Growth Factor and Hormones) 血管內(nèi)皮細(xì)胞生長因子(VEGF)是一種特異作用于血管內(nèi)皮細(xì)胞的多功能細(xì)胞因子,它能引起血管通透性增加,引起細(xì)胞外基質(zhì)成分改變,誘導(dǎo)血管形成.在炎癥、創(chuàng)傷愈合、心臟缺血、動(dòng)脈粥樣硬化、糖尿病性視網(wǎng)膜病變及腫瘤形成等與血管生成和病變有關(guān)的諸多病理過程中起重要作用.
VEGF與血管生成有關(guān),從而也與腫瘤生長也有很大關(guān)系,近年來受到很多關(guān)注.
版權(quán)所有 2004-2026 m.a6308.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
男女无套内射白将在线线国语 | 连续高潮抽搐爽死喷水流白浆无码 | 精品无人区一区二区三区 | 国产精品一区二区在线观看99 | 人妖欧美一区二区三区四区 | 欧洲美女人**一级毛片 | 久久99人妻无码精品一区二区 | 欧美日韩一区精品视频一区二区 | 手机永久免费的AV在线电影网无码 | 台湾一级毛片永久免费 | 美女视频黄a视频全免费网站色窝 | 欧美人与禽zoz0性伦交 | 欧美乱色伦图片区小说 | 痉挛大量潮喷精品无码视频 | 日本午夜精品一区二区三区电影 | 我国产码在线观看AV哈哈哈网站 | 农民人伦一区二区三区 | 国产精品久久久久无毒 | 欧美一区二区三区播放 | 久久久又黄又爽免费观看下载 | 无码AV免费精品一区二区三区 | 熟妇丰满大屁股在线播放BBW | 91桃色污无限免费看 | 亚洲国产精品嫩草影院在线观看 | 国产91色在线综合亚洲 | 色老板最新网站视频地址 | 又大又粗又爽17p | 中文字幕精品久久久人妻特粗粗大 | 一级欧美一级日韩 | 性高湖久久久久久久久 | 国产在线视频欧美一区二区三区 | 绿意盎然侄子小钢炮的成长经历 | 久久精品国产亚洲AV影院 | 忘忧草日本在线播放WWW | 好舒服好粗好硬免费视频 | 内射无码AV-区二区在线观看 | 学生妹无套内射正在播放 | 欧美激情性A片在线观看 | 国产福利91精品一区二区三区 | 免费精品美女久久久久久久久久 | 亚洲国际精品素人AV |